[PDF][PDF] Kinetochore life histories reveal an Aurora-B-dependent error correction mechanism in anaphase

O Sen, JU Harrison, NJ Burroughs, AD McAinsh - Developmental cell, 2021 - cell.com
… because our algorithm is not able to detect lazy kinetochores … We found that the most severe
laziness associates with disrup… merotelic nature of lazy kinetochores is consistent with our

The right place at the right time: Aurora B kinase localization to centromeres and kinetochores

AJ Broad, JG DeLuca - Essays in biochemistry, 2020 - portlandpress.com
Merotelic attachments occur when one sister kinetochore is … at kinetochores, when kinetochores
were properly bi-oriented. … sufficient to recruit Aurora B kinase and its CPC partners [56,…

[HTML][HTML] Aurora B kinase is recruited to multiple discrete kinetochore and centromere regions in human cells

AJ Broad, KF DeLuca, JG DeLuca - Journal of Cell Biology, 2020 - rupress.org
… demonstrating that chromosome bi-orientation results in an increase in the inner-to-outer …
We found that in early mitosis, Aurora B, detected by a pan-Aurora B antibody, localizes …

Untangling the contribution of Haspin and Bub1 to Aurora B function during mitosis

MA Hadders, S Hindriksen, MA Truong… - Journal of Cell …, 2020 - rupress.org
… pole) or merotelic attachments (one kinetochore attached to … However, our findings are
in line with several recent studies … of Aurora B is not a prerequisite for chromosome bi-orientation. …

Dynamics of kinetochore structure and its regulations during mitotic progression

M Hara, T Fukagawa - Cellular and Molecular Life Sciences, 2020 - Springer
… attachment, such as merotelic attachment, as well as … Aurora B kinase (AurB) is an important
kinase controlling the … , and it is suggested that CENP-T associates with H3 nucleosomes on …

[HTML][HTML] Aurora B kinase erases monopolar microtubule-kinetochore arrays at the meiosis I-II transition

S Villa-Consuegra, VA Tallada, J Jimenez - Iscience, 2023 - Elsevier
… Since Aurora B kinase is the enzymatic partner of the … Aurora B controls sister chromatids
mono-orientation and … defects due to the formation of merotelic attachments at MII. …

Identification of a novel nucleolar protein complex required for mitotic chromosome segregation through centromeric accumulation of Aurora B

A Fujimura, Y Hayashi, K Kato, Y Kogure… - Nucleic acids …, 2020 - academic.oup.com
associates with the PR and acts as a binding scaffold for several pre-rRNA processing proteins
(20,33). Consistent with this notion, treatment … attachments and correcting the orientation. …

Aurora B SUMOylation is restricted to centromeres in early mitosis and requires RANBP2

E Di Cesare, S Moroni, J Bartoli, M Damizia… - Cells, 2023 - mdpi.com
… signals using Aurora B and each of its partners, Borealin and … by an increase in merotelic
attachments compared to … The identification of RANBP2 in our study would fulfil that …

The role of Aurora B kinase in normal and cancer cells

E Titova, G Shagieva, V Dugina, P Kopnin - Biochemistry (Moscow), 2023 - Springer
… to borealin and survivin and orientation in the centromere region… Aurora B activity result in
the increased number of merotelic … MYCN is responsible for high levels of Aurora B detected in …

[PDF][PDF] An anaphase surveillance mechanism prevents micronuclei formation from frequent chromosome segregation errors

B Orr, F De Sousa, AM Gomes, O Afonso, LT Ferreira… - Cell Reports, 2021 - cell.com
… whether Aurora B plays a role in anaphase error correction, … forces in the resolution of
merotelic attachments. During this … The recent discovery that Aurora-Bmediated phosphorylation …